Lifting Booster / Skin Booster

A Choice Tailored
to Your Skin.

Rejuran | Rejuran®

A tissue repair biomaterial based on
salmon-derived PN (polynucleotide).
We assess your skin concerns and treatment area
to help identify an approach suited to you.

Skincare editorial of a model touching her cheek against a water-toned background
Model image · Not a treatment result

HERSHE’s Perspective on Rejuran

Before the Name,
We Assess Your Skin Today.

Rejuran is a tissue repair biomaterial based on PN (polynucleotide), produced by purifying and processing DNA derived from salmon germ cells, that acts as a physical scaffold at the injection site.

PN and PDRN are both DNA-derived materials, but they are distinct substances. Rejuran is a PN-based product approved for the temporary improvement of fine lines on the adult face. The medical team will advise on the treatment area and suitability after consultation.

DOT® PN PharmaResearch’s proprietary DNA optimization technology

Product authenticity can be checked using the DOT® marking, QR code, and NFC tag on the package.

Material Base
PN (polynucleotide)
Approved Purpose
Temporary improvement of fine lines on the adult face
Procedure Time · Number of Sessions
Provided after consultation
Individual Plan
Provided after consultation

Treatment at a Glance

Which Skin Concern
Brought You Here?

Explore the options that interest you. Detailed guidance for each is provided below.

Treatment is not determined by a concern alone. The medical team will advise on the treatment area and suitability after consultation.

Product information source: Official PharmaResearch website · Products used in the clinic must be confirmed separately

Rejuran Treatment Guide

A Thoughtful Choice
for Your Skin and Treatment Area.

Profile editorial of a model illuminated by rippling light
We consider the differences between treatment areas, including the eye area.

Time to Understand Your Skin.

Starting with Your Skin Concerns

Rejuran | Rejuran®

This core option uses PN (polynucleotide) as its primary ingredient. Consultation begins with your skin concerns, considers your desired changes and current skin condition, and assesses suitability.

Who May Consider It

Those concerned about facial fine lines or skin texture · Those considering Rejuran for the first time

Pending Detailed Treatment Guidance

Procedure time · Number and interval of sessions · Recovery guidance · Precautions

Reviewing Formulation Differences

Rejuran HB | Rejuran® HB

Officially verified product: Rejuran HB plus · Product used in the clinic requires confirmation

According to official PharmaResearch information, Rejuran HB plus combines PN with hyaluronic acid (HA) and lidocaine. The manufacturer presents it as an option for consultation about crow’s feet wrinkles and hydration; confirm the product used in the clinic and any formulation differences during consultation.

Who May Consider It

Those seeking consultation about crow’s feet wrinkles or hydration · Those who want to review formulation differences

Pending Detailed Treatment Guidance

Ingredients · Treatment area · Number and interval of sessions · Precautions

Eye Area Guidance

Rejuran I | Rejuran® I — Eye Area

This PN-based option focuses consultation on thin skin around the eyes and fine lines beneath the eyes. The medical team separately assesses the eye-area skin and confirms suitability for that area.

Who May Consider It

Those seeking consultation about thin eye-area skin or under-eye fine lines · Those who want focused assessment of the eye area

Pending Detailed Treatment Guidance

Eye-area treatment range · Treatment guidance · Precautions

Concept image of a clear serum droplet against a dark background
Concept image provided to explain the ingredient · Not an actual treatment product or topical skincare product · Model image · Not a treatment result

The Basis of Rejuran

PN

Considering Skin Structure
Through Physical Support.

Polynucleotide (PN)

This tissue repair biomaterial uses PN (polynucleotide), produced by purifying and processing DNA derived from salmon germ cells, as its primary ingredient. It acts as a physical scaffold at the injection site and is approved for the temporary improvement of fine lines on the adult face.

PN and PDRN are both DNA-derived materials, but they are distinct substances. Rejuran uses PN as its primary ingredient.

DOT® PN PharmaResearch proprietary DNA optimization technology

Consult About Rejuran
  • Rejuran
  • Rejuran HB plus
  • Rejuran I

Official PharmaResearch product images · Products used in the clinic must be confirmed separately

  • Physical Support

    Acts as a biomaterial that physically
    supports tissue at the injection site.

  • Salmon-Derived PN

    Uses a material produced by purifying and processing
    DNA derived from salmon germ cells as its primary ingredient.

  • Individual Guidance

    The treatment plan and suitability are explained
    based on your consultation.

Pending Detailed Treatment Guidance

Treatment area · Method · Number and interval of sessions · Recovery guidance · Precautions

HERSHE Consultation Process

From Understanding Your Skin
to Post-Treatment Guidance.

  1. First

    Skin Condition Consultation

    Tell the medical team about your areas of interest, skin concerns, previous treatments, and current medications.

  2. Second

    Review Your Individual Plan

    Review treatment suitability and product-specific guidance. Make your decision after receiving a full explanation of the method and precautions.

  3. Third

    Post-Treatment Guidance

    You will receive guidance on post-treatment care and symptoms that require attention. Contact the clinic with any questions.

Model image · Not a treatment result

Frequently Asked Questions

Questions to Consider
Before Your Consultation.

Please consult the medical team thoroughly before deciding on treatment.

All use PN as their primary ingredient, but their formulations differ. According to official PharmaResearch information, Rejuran HB plus adds hyaluronic acid and lidocaine to PN. Rejuran I is intended for the eye area. The formulation of products used in the clinic requires separate confirmation after consultation.

PN (polynucleotide) and PDRN (polydeoxyribonucleotide) are both DNA-derived materials, but they are distinct substances. Rejuran uses PN as its primary ingredient.

Consultation for Rejuran I focuses on the eye area. After assessing the eye-area skin, the medical team advises on the specific treatment range and suitability.

Treatment-specific information is pending confirmation. Individual plans and recovery may vary, so ask for details during your consultation.

Please share health information the medical team should know, including skin conditions or allergies, current medications, previous treatments, and whether you are pregnant or breastfeeding.

Direct 1:1 consultation

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